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SPR technology platform based on optical surface plasmon resonance (SPR) can perform real-time and label-free monitoring of intermolecular interactions, including affinity, kinetics, active concentration, and thermodynamic effects at the molecular level through intermolecular interaction detection. SPR technology platform is high-throughput and highly sensitive and can provide you with high-accuracy analysis results.

Surface plasmon resonance (SPR) is a technology that relies on a physical optics phenomenon. A thin layer of biomolecular (dielectric medium) such as proteins, nucleic acids, liposomes, protein membranes, carbohydrates or small molecules is immobilized on the surface of the sensor chip. The surface of the chip is connected to a microchannel system by which the flow rate of the buffer and the sample flow through the surface of the dielectric medium are precisely controlled. The interaction of the molecular ligands with the sample (analytes) in a mobile phase solution can lead to the change on the sensor surface that is detected by surface plasmon resonance phenomena. Therefore, the entire process of the sample (analytes) and ligand interaction is recorded in real-time. Information on the affinity, kinetics, selectivity, concentration, and thermodynamics of the ligand molecule binding to the sample can be determined from the experimentally obtained interaction profiles.

Fig.1 The sensing curve and analysis results of molecular interaction analysis of SPR technology platform

Advantages of the SPR technology:

• label-based or label-free analysis
• Low sample requirements, a wide range of application
• low sample consumption and multiplexing analysis
• In-depth, real-time analysis of the natural dynamics of the sample
• High throughput, high sensitivity, and high selectivity analysis
• Stable and repeatable measurements
• Furnish accurate outcomes at a low cost

SPR services can be applied for:

• Real-time, label-free monitoring of biomolecular interaction
• Biological and chemical analyte detection
• High throughput screening of molecules
• Molecular competition testing

In addition, the customizable performance of the SPR technology platform provides you with customizable chip services to meet your various analysis and testing needs. Based on the above advantages, our technology platform can be widely used in these areas, including basic research, biological mechanism research, drug research process, quality analysis, and testing.

Why choose us?

• Years of experience in SPR-based analysis services
• A relatively low-cost, robust multiple analyte detection biosensor platform
• Stable and repeatable measurements
• Reusable and customized sensor chips
• High quality service experience and timely feedback to project progress

We provide a Wide Range of services for You to Choose