SPR Technology for Thermodynamics Analysis

The role of thermodynamic analysis in basic research

The main content of thermodynamic analysis is to study the properties of the material system in equilibrium in thermal phenomena and to establish the equilibrium relationship of energy, as well as the interaction between the system and the outside world when the state changes. The macroscopic theory of thermal phenomena is based on the first law of thermodynamics, the second law of thermodynamics, and the third law of thermodynamics. The macroscopic thermodynamic process is studied through changes in parameters such as the pressure and temperature of substances. Three commonly used thermodynamic analysis methods include enthalpy analysis, entropy analysis and exergy analysis. Through thermodynamic analysis, we can obtain the process of intermolecular energy conversion and the structural mechanism of the strength and speed of the binding capacity.

Figure.1 Simplified diagram of the second law of thermodynamics

Surface plasmon resonance (SPR) system in the process of thermodynamic analysis

• What can we mainly do in the process of thermodynamic analysis

The content of the thermodynamics part has been added to enrich SPR System for the detection of intermolecular interactions. Through our SPR services, you can obtain the thermodynamic parameters of the intermolecular interactions at different temperatures or pressures. Through these thermodynamic parameters, you can carry out a deeper mechanism study of the intermolecular interactions. The determination of the equilibrium state of the intermolecular interaction and the thermodynamic related parameters of the transition state makes the molecular interaction information acquisition results of SPR system more abundant and useful, mainly providing help for the mechanism research in basic research.

• SPR system can provide you with high-qulity thermodynamic analysis

The high throughput of our services can facilitate you to obtain the equilibrium state and transition state thermodynamic parameters of different samples in large quantities in a single run for your sample screening process. The high accuracy and high sensitivity of SPR system provide a guarantee for your thermodynamic measurement results and can greatly minimize errors. The reusable performance of the chip of SPR technology platform on the one hand facilitates the repeatability of the results and reduces the cost for you on the other hand.

Figure.2 BIAchip™ in the process of thermodynamic analysis

Choosing SPR services of Creative Proteomics, you will greatly save time and money costs owing to high-throughput intermolecular interaction detection. All services are available on a 24/7/365 basis. If you have any questions or suggestions about our services, please feel free to contact us right now.

For research use only. Not intended for any clinical use.