Early Diagnosis Reagents for Diseases Based on SPR Technology

The importance of early diagnosis of disease

Early diagnosis of disease is a method of diagnosis and treatment specifically for early patients with major diseases. Its purpose is to detect and treat early, so as to reduce the suffering and economic burden of patients. Let us take cancer disease as an example. The cure rate of cancer in the middle and late stages is extremely low. At the same time, cancer patients have to endure a lot of pain during the treatment process without knowing whether it can be cured. Therefore, realizing early detection and early treatment of diseases is the key task and goal of biomedical workers. The following are two examples of early detection applications.

• Detection of disease markers

As more and more attention is paid to the research on the biological mechanism of diseases, more and more disease-related targets and biological markers have been developed. Biomedical workers can indirectly detect diseases by detecting some biomarkers in body fluids (such as blood and urine), and conduct preliminary screening for diseases at the same time. For example, the initial screening of cancer is mainly to detect the corresponding cancer markers, while chronic diseases need to detect the content of certain metabolic indicators in the body, such as carbohydrates. Intermolecular interaction analysis can realize the preliminary screening of diseases through concentration analysis.

• Pregnancy testing

The detection of intermolecular interactions can also be applied to the inspection process during pregnancy. On the one hand, the diagnostic project is about the identification of pregnancy. This process determines whether a woman is pregnant or not by detecting changes in the hormone and protein content in the body fluid of the pregnant woman. On the other hand, intermolecular interaction analysis can also be applied to the process of prenatal diagnosis. Before a child is born, it is usually necessary to detect and diagnose the developmental status of the fetus.

Surface plasmon resonance (SPR) in the development of early diagnosis reagents

The early diagnosis of disease is of great significance, which is beneficial to greatly improve the cure rate of the disease, and realize early detection, early treatment and early recovery. Therefore, the development of early diagnosis reagents for diseases has been given more and more attention. SPR technology can realize the development of diagnostic reagents based on the interaction detection of multiple biologically active molecules, such as proteins. In the development process of diagnostic reagents, the detection content of SPR technology mainly includes the analysis of affinity and kinetics. In one run, the high-throughput technology platform can detect hundreds of samples in parallel. SPR can not only improve the detection efficiency, but also realize the repeatability of the research and development process. The high-throughput technology platform simplifies the research process and reduces the time of repetitive work. In addition, the SPR technology platform can ensure the accuracy and sensitivity of the entire analysis and detection process, effectively avoiding major errors such as misdiagnosis. In the development of diagnostic reagents for diseases, our SPR technology platform is your most convenient and efficient choice.

Fig.1 BIAchip^TM in the development of early diagnosis reagents 

Choosing SPR technology platform of Creative Proteomics, you will greatly save time and money costs owing to high-throughput intermolecular interaction detection. All services are available on a 24/7/365 basis. If you have any questions or suggestions about SPR, please feel free to contact us right now.

For research use only. Not intended for any clinical use.