Immunology Mechanism Research Based on SPR Technology

The research significance of immunological mechanism

Immunity is the biological effect produced by the body in the process of recognizing itself and eliminating dissidents. The immune system protects the body by identifying and attacking non-self foreign cells, while minimizing damage to its own healthy cells. The key point of the immune system is to distinguish between self and non-self. The key elements in the process of identifying self and non-self are antigens, small molecules and peptides that induce immune responses. The immune system has three main functions, including immune defense (the ability to defend against pathogenic microorganisms, which is related to immunodeficiency diseases), immune homeostasis (the ability to remove damaged or senescent cells, which are related to autoimmune diseases), and immune surveillance (It can remove cells that copy errors and mutated cells, which are related to cell canceration and persistent infection). The research on the mechanism of immunology mainly revolves around the following aspects:

1. Specific prevention and treatment based on the specificity of immune response and immune tolerance provide treatment options, while improving efficiency and reducing side effects.

2. Development and application of antibody cDNA expression library, phage display library and proteomics.

3. Development of immune drugs.

4. Development of new antibacterial and immune-enhancing antibiotics.

Figure.1 Schematic diagram of viruses attacking cells and macrophages attacking viruses acting on the human immune system

Surface plasmon resonance (SPR) in immunological mechanism research

From the study of pathogenesis and drug identification in clinical trials, the analysis of intermolecular interactions occupies the entire process of exploring biological mechanisms and applications. From pathogenesis research and drug identification in clinical trials, the analysis of molecular interactions runs through the entire process of exploring biological mechanisms and applications. The interaction of the immune system's own molecules and molecules, between cells and cells, between the immune system and the body's various systems, builds the basic framework of the immune system.

Fig.2 BIAchip™ in the process of immunological mechanism research 

Based on the picture above, our SPR technology platform can provide high-throughput intermolecular interaction detection for your intermolecular interaction detection in the process of immunology-related biological mechanism research. In a single run, hundreds or thousands of samples can be analyzed at the same time, which greatly saves your time. Based on the reusability of the chip, you don't need to worry about cost. Most importantly, we can be responsible for helping you design and customize a chip that meets your experimental purpose based on the superior flexibility of the SPR technology platform.

Please select the service you require in relation to the analysis of immunological mechanisms.

• Cytokine Detection Service Based on SPR
• Immune Checkpoint Protein Analysis Service Based on SPR
• Fc Receptor-mediated Immune Mechanisms Analysis Service Based on SPR

Choosing SPR technology platform of Creative Proteomics, you will greatly save time and money costs owing to high-throughput intermolecular interaction detection. All services are available on a 24/7/365 basis. If you have any questions or suggestions about SPR, please feel free to contact us right now.

For research use only. Not intended for any clinical use.