Types of Chips in SPR Technology

Chip-based intermolecular interaction detection

In the field of basic biology research, the study of molecular interactions has become more and more extensive, and more and more attention has been paid. Analyzing the interaction between molecules is the basis for revealing the structure and function of biomolecules that determine macroscopic life phenomena. Although some active molecules can function in the form of monomers, most active molecules function in the form of intermolecular interactions or complexes. Traditional intermolecular interaction detection is low-throughput and low-sensitivity, and the entire detection process is too time-consuming and costly. The emergence of the chip solves the problem of low throughput which allowing parallel detection in many sample wells without interfering with each other. Our technology platform has higher sensitivity and higher selectivity in sample detection while ensuring high throughput. The coverage of the applicable types of our chips is very wide, which will be introduced next.

Types of Chips in SPR we can provide for you

SPR is a technology platform for high-throughput measurement of interactions. Through this technology platform, you can quickly obtain a data curve of interactions between biomolecules. Through this data curve, affinity, kinetics, specificity, concentration, thermodynamics, and multiple binding information of the ligand molecule and the sample to be tested can be determined. As you can see in the figure below, the range of samples that SPR technology platform can detect almost covers all biomolecules. The detection of the following biologically active molecules can be achieved through SPR technology platform. If your project has related testing requirements for the following molecules, please feel free to contact us.

Figure.1 The testing sample coverage of BIAchip™ technology platform

Based on the extensive sample coverage of SPR technology platform, Creative Proteomics provides you with the following types of chips that you can choose from, Including standardized template chips and customized template chips for special testing.

• Protein - protein interaction chip
• Protein - DNA interaction chip
• Protein - small molecule interaction chip
• Antigen - antibody interaction chip
• Enzyme - substrate interaction chip
• Customized chips(For your specific measurement needs, Creative Proteomics can provide solutions for your review within 1-2 days in which provide you with exclusive custom chips)

Choosing SPR technology platform of Creative Proteomics, you will greatly save time and money costs owing to high-throughput intermolecular interaction detection. All services are available on a 24/7/365 basis. If you have any questions or suggestions about SPR, please feel free to contact us right now.

For research use only. Not intended for any clinical use.