Protein-Virus, Particle or Bacterium Interaction Chip

Category
Covalently coupled biosensor chip

Description
Carboxymethyl dextran surfaces are very stable and resistant to the non-specific binding of biomolecules. The dextran layer is in the form of a highly flexible non-cross-linked brush-like structure extending 100 to 200 nanometers from the surface. The flexible nature of the dextran contributes to the accessibility of binding sites on an immobilized ligand. Planar carboxymethyl dextran coating (less than 5 nm) allows the immobilization of ligands in a single monolayer.

Feature
2D planar carboxymethyldextran surface, <5nm coating thickness
Covalent coupling
Recommended for the binding of high molecular weight analytes such as antibodies or nanoparticles
The CMDP coating is also suitable for particulate analytes, such as viruses and whole cells

Category
Covalently coupled biosensor chip

Description
Carboxymethyl dextran surfaces are very stable and resistant to the non-specific binding of biomolecules. The dextran layer is in the form of a highly flexible non-cross-linked brush-like structure extending 100 to 200 nanometers from the surface. The flexible nature of the dextran contributes to the accessibility of binding sites on an immobilized ligand. 3D carboxymethyl dextran sensors coated with dextran hydrogel layer of low, medium or high density. Medium-high density, 50 nm coating thickness.

Feature
High binding capacity
Produces highly stable covalent bond
3D carboxymethyl dextran sensors with medium density are recommended for most biological assays like protein-small molecule or protein-protein interactions

Category
Covalently coupled biosensor chip

Description
Polycarboxylate hydrogel sensor chip. 30 nm coating thickness.

Feature
Use for large/medium sized molecules and low molecular weight molecules
Provides another choice for high capacity coupling when studying protein-small molecule interactions or when dextran is not ideal