Lipid-related Interactions Analysis Service Based on SPR Technology

Lipids are one of the important nutrients needed by the human body. They provide the energy and essential fatty acids needed by the body, and are the constituents of the body's cell tissues. The occurrence and development of diseases such as hyperlipidemia and atherosclerosis are all related to phospholipids. Phospholipids, as a kind of lipids, are an important part of biological membranes, which occupy an important position in the basic research of biology. Because cells are the basic unit of living organisms, and biological membranes are an important part of cells, so research based on phospholipids is also very necessary.

Fig.1 The schematic diagram of the basic structure of phospholipids as an important part of biological membranes

Phospholipids are complex lipids that contain phosphoric acid. As shown in the figure above, phospholipids are amphiphilic molecules with a hydrophilic nitrogen or phosphorus-containing head at one end and a hydrophobic (lipophilic) long hydrocarbon-based chain at the other end. When the hydrophilic ends of the phospholipid molecules are close to each other, and the hydrophobic ends are close to each other, a phospholipid bilayer is formed. On this basis, protein, glycolipid, cholesterol and other molecules are added to form the basic framework of cell membranes.

Surface plasmon resonance (SPR) technology platform in the analysis service of lipid-related molecular interactions

The main component is the phospholipid bilayer biomembrane as the most basic component of the cell, which is a barrier separating the inside and outside of the cell. The fluidity of phospholipid bimolecules is related to the exchange of substances between cells and the outside world. For example, cells can take up needed substances through endocytosis and discharge metabolic waste products through exocytosis. Because cells are the basic building blocks of living organisms, the analysis of lipid-related molecular interactions is very important in the basic research of biological membranes. Our SPR technology platform can provide high-throughput lipid-related molecular interaction analysis services, as shown in the figure below.

Fig.2 BIAchip^TM in the analysis service of lipid-related molecular interactions

There are interactions between biofilms and various substances inside and outside the cells, and these interactions directly or indirectly regulate the various physiological activities and functions of living bodies. Our SPR technology platform can provide high-throughput services for lipid-related molecular interaction analysis. In a single run, SPR technology can analyze hundreds of samples in parallel at the same time. SPR provides you with a repeatable experiment platform, which promotes the entire process of your project and reduces costs to a certain extent. In addition, the accuracy and sensitivity of SPR technology provide guarantee for the results of your lipid-related molecular interaction analysis.

• Detectable lipid-related molecular interaction analysis of samples based on SPR

Since biological membranes occupy most of the structural composition of cells, the detection objects of lipid-related molecular interaction analysis must be diverse. Therefore, basic requirements are put forward for the detection of lipid-related intermolecular interactions. Our SPR technology platform can fully meet this requirement, and achieve full coverage of various types of test samples as much as possible. SPR technology does not have high requirements for the form of the tested sample. As long as you need, our SPR technology platform can achieve customized services. Our SPR technology platform can provide corresponding customized services for the detection of various samples, including antibodies, antigens, small organic molecules, bacteria, viruses, tissue lysates, serum, ascites, etc.

• Available chip types for lipid-related molecular interaction analysis based on SPR

Creative Proteomics has a professional scientific research team in the field of biology, which can provide you with consulting and customized services for the analysis of lipid-related molecular interactions. After receiving your order, we will immediately arrange for you to have experts in related fields to communicate with you in detail. After understanding your specific needs, you will receive a customized solution within 1-2 days. You don't need to worry about the issue of delivery time, because providing you with efficient service is our most important advantage all the time. For lipid-related molecular interaction analysis, we provide the following lipid-related molecular interaction services.

If you do not find the service you are interested in, please contact us for exclusive customized services. All services of Creative Proteomics are available on a 24/7/365 basis.

For research use only. Not intended for any clinical use.